History
The modern cleanroom was invented by American physicist Willis Whitfield. An employee of the Sandia National Laboratories, Whitfield created the initial plans for the cleanroom in 1960. Prior to Whitfield's invention, earlier cleanrooms often had problems with particles and unpredictable airflows. Whitfield designed his cleanroom with a constant, highly filtered air flow to flush out impurities.Within a few years of its invention in the 1960s, sales of Whitfield's modern cleanroom had generated more than $50 billion in sales worldwide. The cleanroom eventually entered the hospital industry in the United Kingdom, primarily in hospital pharmacies